The Seg-Flow® Automated On-line Sampling System provides multiple bioprocess monitoring and control solutions for improving process performance. The Seg-Flow system's patented Segmented On-line Sampling™ technology allows rapid and accurate sampling for 8 vessels or process streams and sample delivery to 4 analyzers and/or fraction collectors. Several feed control options are available with the Seg-Flow system, which can control 2 pumps per vessel. Existing off-line and at-line analytics are seamlessly integrated into a multi-functional on-line PAT tool through the Seg-Flow system’s communication interface and FlowWeb™ control software. The FlowWeb software simultaneously acquires all integrated instrument data and can export the data to any OPC-enabled SCADA for enhanced process monitoring and control.
Sampling Solutions
- Rapid and accurate sampling
- Sample from 1-8 vessels/process streams
- Deliver samples to 4 analyzers/fraction collectors
- Withdraw cell-free or cell-containing samples
- On-line monitoring of nutrients, metabolites & cell growth
- Sample line is cleaned and/or sterilized after every sample
Instrument Integrations
- Agilent® Infinity 1200 Series HPLC
- Cedex Bio HT
- Cedex HiRes Cell Analyzer
- Mettler-Toledo Balances
- Nova® BioProfile® Flex II, Flex, Basic, 100, 300, & 400 analyzers
- Vi-CELL® XR Cell Analyzer
- Waters Acquity UPLC
- YSI® 2700, 2900, 2950, & 7100 Biochemistry Analyzers
Feed Control Options
- Control 2 feed pumps per vessel
- Setpoint control, gravimetric feed control
- Other feed algorithms can be programmed
- Pump interfaces include: Watson-Marlow, Cole-Parmer®, MasterFlex®, SciLog® ACCU Digital, & Ivek
- Other pump interfaces available upon request
SCADA Integrations
- Sartorius BioPAT® MFCS
- DASGIP DASware
- New Brunswick BioCommand®
- Broadley-James BioNet®
- Emerson Delta V
- Other devices and SCADA available upon request
Communication Interfaces
- TCP/IP
- Serial – RS-232
- Analog I/O
- OPC
Your Automated On-Line Bioprocess Sampling Solutions
Economical
Single-use fluid path
Sampling for 1-2 reactors
10” W x 7” H x 10” D
(25.4 cm x 17.8 cm x 25.0 cm)
Single-use fluid path
Sampling for up to 8 reactors
11”W x 10 ¼”H x 14”D
(27.9 cm x 26.0 cm x 35.6 cm)
Chemically inert fluid path
Sampling for up to 8 reactors
11”W x 10 ¼”H x 14”D
(27.9 cm x 26.0 cm x 35.6 cm)
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