預充填純化管柱  |生技/製藥下游製程相關|純化/濃縮

預充填純化管柱


Use of pre-packed columns in downstream chromatography has increased in response to the needs of multi-product facilities and initiatives focused on reducing change-over time.




OPUS® Pre-packed Chromatography Columns 預充填純化層析管柱
Leader of the Pack from bench-scale to production-scale.
Repligen OPUS
設計獎項 / Awards

OPUS® Columns win awards for industrial design excellence

 
iF DESIGN AWARD
2016
  GOOD DESIGN Award
2015
  CORE77 DESIGN AWARD
2015
iF DESIGN AWARD 2016   GOOD DESIGN Award 2015   2015 CORE77 DESIGN AWARD
Winner for Design Excellence - Product   Winner for Design Excellence - Industry   Notable Mention for Design Excellence - Commercial Equipment
純化樹脂 / Resins Selection

Select from over 300 resins to pack into OPUS® PD Columns for Process Development.

Repligen OPUS Resins Selection
技術原理 / Technology

Repligen OPUS Technology

OPUS® columns are the result of expert engineering combined with deep industry knowledge and experience in downstream chromatography.

  • Unique design features
  • Reliable multi-cycle performance
  • Robust GMP-compliant construction
  • Easy cleaning and sanitization
  • Scalable performance consistent across different sizes
  • Performance maintained after shipping
經濟效益 / Economics

Over 19% cost savings and up to 50% labor savings (~92 FTE hours) were achieved when using the OPUS® 60 column compared to traditional self-packed columns.


Repligen OPUS Economics

Glass column amortized over 20 campaigns, OPUS® column over 3 campaigns; 3 batches/campaign; 2 cycles/batch; no column repacks.

Substantial savings are realized because OPUS® columns offer the benefits that come with pre-packed technology:

  • No upfront capital expenses
  • Reduction of CIP and cross contamination
  • Faster campaign turnaround time
  • Operational excellence (reduce labor requirements)

Data presented are estimates and subject to change

OPUS® Columns pre-packed with CaptivA® Protein A Resin
 
OPUS® Columns pre-packed with CaptivA® Protein A Resin
OPUS® Columns pre-packed with CaptivA® Protein A Resin

OPUS® chromatography columns are available pre-packed with CaptivA® resin, combining the superior process economics of CaptivA® resin with ready-to-use convenience and flexible column size options.


OPUS® Columns Application
OPUS® Columns for process development (Atoll columns)

OPUS® Pre-packed Columns for process development, formerly Atoll pre-packed columns, are designed for use in every step during downstream process development, including screening, process validation including viral clearance, scale-up and sample preparation.

OPUS® Columns for process development (Atoll columns)
  • OPUS® RoboColumn for automated parallel chromatography
  • OPUS® MiniChrom for process development
  • OPUS® ValiChrom for process validation, including viral clearance
  • OPUS® 5 for scale-up
  • OPUS® CentriColumn for centrifuge sample preparation
  • OPUS® PipetColumn for manual sample preparation

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預充填純化管柱

Use of pre-packed columns in downstream chromatography has increased in response to the needs of multi-product facilities and initiatives focused on reducing change-over time.

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