預充填純化管柱(Pre-packed chromatography columns)
        


OPUSR Pre-packed Chromatography Columns

Leader of the Pack.
With the broadest selection from bench-scale to production-scale, OPUS? columns are ready-to-use pre-packed alternatives to self-packed columns.
•產品說明
   

OPUS ® Pre-packed Chromatography Columns



list of chromotgraphy resins

Select from over 300 resins to pack into OPUS® PD Columns for Process Development.


Technology
 
OPUS Pre-packed Column

OPUS® columns are the result of expert engineering combined with deep industry knowledge and experience in downstream chromatography.

  • Unique design features
  • Reliable multi-cycle performance
  • Robust GMP-compliant construction
  • Easy cleaning and sanitization
  • Scalable performance consistent across different sizes
  • Performance maintained after shipping

OPUS ® Columns for production-scale 1000L-2000L bioreactor harvests
 
OPUS 45 cm and 60 cm pre-packed columns

OPUS® 45 cm and 60 cm ID columns are the first and only pre-packed columns designed to meet the chromatography requirements of larger 1000L and 2000L single-use bioreactors.

  • Easily configured for bed height, resin, and application
  • Seamless scale-up from smaller ID columns
  • Complete documentation package for GMP use
  • Significant time and cost savings compared to conventional column technology

OPUS ® Columns for GMP manufacturing
 
OPUS column packing

OPUS® columns are designed for use in GMP environments for the manufacturing  of clinical and commercial biologic drugs.

  • Packed in ISO Class 7 clean rooms
  • Complete Regulatory Support File
  • Certificate of Analysis for each column configuration

OPUS ® Columns for process development (Atoll columns)
 

OPUS® Pre-packed Columns for process development, formerly Atoll pre-packed columns, are designed for use in every step during downstream process development, including screening, process validation including viral clearance, scale-up and sample preparation.

  • OPUS® RoboColumn  for automated parallel chromatography
  • OPUS® MiniChrom  for process development
  • OPUS® ValiChrom  for process validation, including viral clearance
  • OPUS® 5 for scale-up
  • OPUS® CentriColumn for centrifuge sample preparation
  • OPUS® PipetColumn for manual sample preparation

Economics
 

Over 19% cost savings and up to 50% labor savings (~92 FTE hours) were achieved when using the OPUS® 60 column compared to traditional self-packed columns. 

45_60_savings.jpg

Glass column amortized over 20 campaigns, OPUS® column over 3 campaigns; 3 batches/campaign; 2 cycles/batch; no column repacks.

 

Substantial savings are realized because OPUS® columns offer the benefits that come with pre-packed technology:

  • No upfront capital expense
  • Reduction of CIP and cross contamination
  • Faster campaign turnaround time
  • Operational excellence (reduce labor requirements)

Data presented are estimates and subject to change.

Use the OPUS® Calculator to find out how much you can save when using OPUS® columns in your specific application.  
•產品規格
   

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